Two graphs $G$ and $H$ are homomorphism indistinguishable over a graph class $\mathcal{F}$ iff $G$ and $H$ admit the same number of homomorphisms from every $F \in \mathcal{F}$.
Many well-studied graph isomorphism relaxations can be characterised as homomorphism indistinguishability relations over natural graph classes.
This website lists properties of graph classes and their homomorphism indistinguishability relations.
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